Author: Jeb Kinnison

Mostly harmless purveyor of gently-used memes. My latest book: "Red Queen: The substrate Wars," available at: http://www.amazon.com/gp/product/B00QSP3JTU/ref=as_li_tl?ie=UTF8&camp=1789&creative=390957&creativeASIN=B00QSP3JTU&linkCode=as2&tag=jebkinn-20&linkId=L5XO3S3LGKGGDT4B. Also see, "Bad Boyfriends: Using Attachment Theory to Avoid Mr. (or Ms.) Wrong and Make You a Better Partner," is now on sale exclusively for Kindle (this will change soon.) Get it at: http://www.amazon.com/dp/B00IW6JYV0

Vitamin D: Anti-Dementia?

Vitamin D

Vitamin D


Via Instapundit, “New Study Supports Links Between Dementia And Vitamin D Deficiency” in IFLScience:

Adding to an ever-growing body of evidence, a new study has found that vitamin D deficiency is associated with a substantially increased risk of developing Alzheimer’s and dementia. While previous studies have drawn similar conclusions, this is the largest, most robust study carried out to date. The results have been published in the journal Neurology.

Vitamin D is an essential vitamin that is produced by the body upon exposure of the skin to sunlight, but it can also be found in small amounts in certain foods such as oily fish. It plays a variety of roles in the body and over recent years our understanding of how it helps to maintain optimum health has dramatically increased. For example, it’s thought to reduce the risk of certain bone diseases, bacterial and viral infections and autoimmune diseases.

Interestingly, some studies have hinted that vitamin D may play a neuroprotective role. In support of this idea, several recent studies have found links between vitamin D deficiency and the risk of dementia and cognitive decline. However, one study also found no associations in men.

To find out more, an international team of researchers, headed by scientists at the University of Exeter, enrolled 1,658 adults aged 65 and over who were able to walk unaided and were free from dementia, cardiovascular disease and stroke. Vitamin D levels were assessed at the start of the study and the participants were then followed for six years in order to investigate who went on to develop Alzheimer’s or other forms of dementia.

The researchers discovered that participants with a moderate vitamin D deficiency had a 53% increased risk of developing any form of dementia, and those with a severe deficiency had a 125% increased risk. Similar results were also found for the risk of developing Alzheimer’s, which is the most common form of dementia. Interestingly, they found that there was a threshold level of 50nmol/L vitamin D in the serum, below which the risk of dementia and Alzheimer’s was markedly increased.

While this shows vitamin D deficiency is associated with increased risk of dementia, it does not prove causation; it’s possible that since oily fish contain lots of D, the Omega-3 fatty acids and other components of fish oil, which has already been shown to reduce dementia, are responsible, since people who regularly eat oily fish won’t suffer D deficiencies. And any number of other cofactors may play a role.

What’s the story on vitamin D supplements? A few years ago, medical professionals themselves were taking 2000-4000 IUDs every day believing these larger doses would be protective against a variety of degenerative diseases. The evidence since is inconclusive. Here are some studies:

Vitamin D and Cardiometabolic Outcomes: A Systematic Review
Vitamin D and calcium: a systematic review of health outcomes.
Vitamin D supplementation for prevention of mortality in adults.
The effect of vitamin D supplementation on skeletal, vascular, or cancer outcomes: a trial sequential meta-analysis

For more on supplements and life-extending habits:

Getting to Less Than 10% Body Fat Like the Models – Ask Me How!
Low-Dose Aspirin Reduces Pancreatic Cancer
Daily Aspirin Regimen Reduces Cancer Rates
Almonds: Superfood, Eat Them Daily for Heart Health
Fish Oil Supplements Ward Off Dementia
Lower Back Pain: Acetaminophen (Tylenol, Paracetamol) Useless
Cleanses and Detox Diets: Quackery
Gluten-Free Diets: The Nocebo Effect
Scams: Multi-Level Marketing, Herbalife
Fish and Fish Oil for Better Brain Health
Salt: New Research Says Too Little May Be Unhealthy

Fish and Fish Oil for Better Brain Health

Costco Canned Salmon Filet

Costco Canned Salmon Filet

Previously I posted about studies showing regular fish oil supplements could help ward off dementia.

The Atlantic in a “This is Your Brain on Fish” by James Hamblin covers the evidence that regular consumption of baked or broiled fish having similar positive effects on brain tissue and functioning:

Dr. Cyrus Raji, a resident radiologist at UCLA, appreciates value beyond the cosmetics of a thick cerebral cortex. He’s the lead researcher in a new study in the current American Journal of Preventive Medicine that found that people who regularly eat fish have more voluminous brains than those who do not—in such a way that stands to protect them from Alzheimer’s disease.

“Understanding the effects of fish consumption on brain structure is critical for the determination of modifiable factors that can decrease the risk of cognitive deficits and dementia,” Raji and colleagues write. The team has previously shown gainful effects of physical activity and obesity on brain structure.

This study found that eating fish—baked or broiled, never fried—is associated with larger gray matter volumes in brain areas responsible for memory and cognition in healthy elderly people.

“There wasn’t one type of fish that was the best,” Raji told me by phone, probably while eating fish. “All that mattered was the method of preparation.” Fried fish had a unique dearth of benefits to the brain.

People who eat fish at least once a week have larger gray matter volumes in the red/yellow areas. “If you eat fish just once a week, your hippocampus—the big memory and learning center—is 14 percent larger than in people who don’t eat fish that frequently. 14 percent. That has implications for reducing Alzheimer’s risk,” Raji said. “If you have a stronger hippocampus, your risk of Alzheimer’s is going to go down.”

“In the orbital frontal cortex, which controls executive function, it’s a solid 4 percent,” Raji said. “I don’t know of any drug or supplement that’s been shown to do that.”

Speaking of supplements, the researchers initially looked to omega-3 fatty acids as the driver of these benefits. But when they looked at the levels of omega-3s in people’s blood, they didn’t correlate with better brain volumes.

“These findings suggest additional evidence that it is lifestyle factors—in this case, dietary intake of fish,” the researchers write, “and not necessarily the presumed biological factors that can affect the structural integrity of the brain.”

Omega-3 fatty acids have previously been shown to slow cognitive decline. In one study, higher levels of omega-3 fatty acids in people’s blood were associated with lower rates of brain atrophy observable over just a four-year period. We also know that when rats are fed diets low in omega-3 fatty acids, they have increased signs of dementia, possibly mediated by insulin and related buildup of amyloid plaques in their tiny brains.

Eating more omega-3 fatty acids, a lot of fruit, and not much meat, has previously been associated with increased volume throughout the brain’s gray matter. Recent research in the journal Neurology found that elderly people with high levels of omega-3 fatty acids in their blood had better cognitive function than those with lower levels. MRIs of their brains showed larger volumes, too. (The associations also held for vitamins B1, B2, B6, B12, C, D, and E, and folate.)

Drs. Deborah Barnes and Kristine Yaffe at UCSF recently calculated in Lancet Neurology that up to half of cases of Alzheimer’s disease “are potentially attributable” to seven modifiable risk factors: diabetes, midlife high blood pressure, midlife obesity, smoking, depression, cognitive inactivity or low educational attainment, and physical inactivity. Minimal inroads in those areas, they say, could result in millions fewer cases of Alzheimer’s.

People who ate fish once per week were just as well off as those who ate it more frequently.
Researchers at the University of Pittsburgh School of Medicine corroborate, “Our research has consistently shown that it is the interactions among these risk factors with the patho-biological cascade of Alzheimer’s disease that determine the likelihood of a clinical expression as dementia or mild cognitive impairment.”

Specific suspects in the fish-brain benefit paradigm are omega-3s docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), which seem to increase the size of the amygdala and anterior cingulate gyrus, and possibly overall brain volume. DHA and EPA can also affect the way neural synapses fire.

I have a can of Costco salmon filet every day for lunch; it’s an easy, delicious way to both meet protein needs and consume the healthy fish oils that protect and increase brain power.

Fish Oil Supplements Ward Off Dementia

For more on good supplements and life-extending habits:

Getting to Less Than 10% Body Fat Like the Models – Ask Me How!
Low-Dose Aspirin Reduces Pancreatic Cancer
Daily Aspirin Regimen Reduces Cancer Rates
Almonds: Superfood, Eat Them Daily for Heart Health
Fish Oil Supplements Ward Off Dementia
Lower Back Pain: Acetaminophen (Tylenol, Paracetamol) Useless
Cleanses and Detox Diets: Quackery
Gluten-Free Diets: The Nocebo Effect
Scams: Multi-Level Marketing, Herbalife
Vitamin D: Anti-Dementia?
Salt: New Research Says Too Little May Be Unhealthy

Why Did Black Crime Syndicates Fail to Go Legit?

Black Guerrilla Gang

Black Guerrilla Gang

Malcolm Gladwell has an interesting long essay in The New Yorker about the gradual going-straight and assimilation into respectable society of the Italian crime families (“Mafia”) of the 50s.

The Lupollos were not really called the Lupollos, of course; nor was Uncle Phil really named Philip Alcamo. Ianni changed names and identifying details in his published work. The patriarch of the Lupollo clan he called Giuseppe. Giuseppe was born in the eighteen-seventies in the Corleone district of western Sicily. He came to New York in 1902, with his wife and their two young sons, and settled in Little Italy. He imported olive oil and ran an “Italian bank,” which was used for loan-sharking operations. When a loan could not be repaid, he would take an equity stake in his debtor’s business. He started a gambling operation, and moved into bootlegging; during Prohibition, the business branched out into trucking, garbage collection, food products, and real estate. He recruited close relatives to help him build his businesses—first, his wife’s cousin Cosimo Salemi, then his son, Joe, then his daughter-in-law’s brother, Phil Alcamo, and then the husband of his granddaughter, Pete Tucci. “From all accounts, he was a patriarch, at once kindly and domineering,” Ianni wrote of Giuseppe. “Within the family, all important decisions were reserved for him. . . . Outside of the family, he was feared and respected.” The family moved from Little Italy to a row house in Brooklyn, and from there—one by one—to Queens and Long Island, as its enterprise grew to encompass eleven businesses totalling tens of millions of dollars in assets.

“A Family Business” was the real-life version of “The Godfather,” the movie adaptation of which was released the same year. But Ianni’s portrait was markedly different from the romanticized accounts of Mafia life that have subsequently dominated popular culture. There were no blood oaths in Ianni’s account, or national commissions or dark conspiracies. There was no splashy gunplay. No one downed sambuca shots at Jilly’s, on West Fifty-second Street, with Frank Sinatra. The Lupollos lived modestly. Ianni gives little evidence, in fact, that the four families had any grand criminal ambitions beyond the illicit operations they ran out of storefronts in Brooklyn. Instead, from Giuseppe’s earliest days in Little Italy, the Lupollo clan was engaged in a quiet and determined push toward respectability.

By 1970, Ianni calculated, there were forty-two fourth-generation members of the Lupollo-Salemi-Alcamo-Tucci family—of which only four were involved in the family’s crime businesses. The rest were firmly planted in the American upper middle class. A handful of the younger members of that generation were in private schools or in college. One was married to a judge’s son, another to a dentist. One was completing a master’s degree in psychology; another was a member of the English department at a liberal-arts college. There were several lawyers, a physician, and a stockbroker. Uncle Phil’s son Basil was an accountant, who lived on an estate in the posh Old Westbury section of Long Island’s North Shore. “His daughter rides and shows her own horses,” Ianni wrote, “and his son has some reputation as an up-and-coming young yachtsman.” Uncle Phil, meanwhile, lived in Manhattan, collected art, and frequented the opera. “The Lupollos love to tell of old Giuseppe’s wife Annunziata visiting Phil’s apartment,” Ianni wrote. “Her comment on the lavish collection of paintings was ‘manga nu Santa’ (‘not even one saint’s picture’).”

The moral of the “Godfather” movies was that the Corleone family, conceived in crime, could never escape it. “Just when I thought I was out,” Michael Corleone says, “they pull me back in.” The moral of “A Family Business” was the opposite: that for the Lupollos and the Tuccis and the Salemis and the Alcamos—and, by extension, many other families just like them—crime was the means by which a group of immigrants could transcend their humble origins. It was, as the sociologist James O’Kane put it, the “crooked ladder” of social mobility.

The piece has more interesting material about the Italian crime family’s climb to respectability. Gladwell highlights another book to ask the differential question: why were the black drug gangs of the 70s-90s not able to make the same transition? It may be that declining police corruption, and a lack of political friends in high places to protect their underground business, kept them from getting any traction in the upward climb:

Fast-forward two generations and, with any luck, the grandchildren of the loan sharks and the street thugs would be riding horses in Old Westbury. It had happened before. Wouldn’t it happen again?

This is one of the questions at the heart of the sociologist Alice Goffman’s extraordinary new book, “On the Run: Fugitive Life in an American City.” The story she tells, however, is very different.

….

Chuck and Mike were criminals: they were complicit in the barbarism of the drug trade. But, in the Mertonian sense, they were also innovators. Goffman describes how they craved success in mainstream society. They tried to get an education and legitimate jobs, only to find themselves thwarted. Selling crack was a business they entered into only because they believed that all other doors were closed to them. In Chuck’s case, his mother had a serious crack habit. He began dealing at thirteen in order to buy food for the family and to “regulate” his mother’s addiction; if he was her supplier, he figured, she wouldn’t have to turn tricks or sell household possessions to pay for drugs. Chuck’s criminal activities were an attempt to bring some degree of normalcy to his family.

The problem was that on 6th Street crime didn’t pay. Often, Chuck and Mike had no drugs to sell: “their supplier had gotten arrested or was simply unavailable, or the money they owed this ‘connect’ had been seized from their pockets by the police during a stop and search.” And, if they did have drugs, the odds of evading arrest were small. The police saturated 6th Street. Each day, Goffman saw the officers stop young men on the streets, search cars, and make arrests. In her first eighteen months of following Mike and Chuck, she writes:

I watched the police break down doors, search houses and question, arrest, or chase people through houses fifty-two times. Nine times, police helicopters circled overhead and beamed searchlights onto local streets. I noted blocks taped off and traffic redirected as police searched for evidence . . . seventeen times. Fourteen times during my first eighteen months of near daily observation, I watched the police punch, choke, kick, stomp on, or beat young men with their nightsticks.

Years later, when Chuck went through his high-school yearbook with Goffman, he identified almost half the boys in his freshman class as currently in jail or prison. Between the ages of twenty-two and twenty-seven, Mike had spent three and a half years behind bars. He was on probation or parole for eighty-seven weeks of the hundred and thirty-nine weeks that he was out of prison, and made fifty-one court appearances.

The police buried the local male population under a blizzard of arrest warrants: some were “body” warrants for suspected crimes, but most were bench and technical warrants for failure to appear in court or to pay court fees, or for violations of probation or parole. Getting out from under the weight of warrants was so difficult that many young men in the neighborhood lived their lives as fugitives. Mike spent a total of thirty-five weeks on the run, steering clear of friends and loved ones, moving around by night. The young men of the neighborhood avoided hospitals, because police officers congregate there, running checks on those seeking treatment for injuries. Instead, they turned to a haphazard black market for their medical care. The police would set up a tripod camera outside funerals, to record the associates of young men murdered on the streets. The local police, the A.T.F., the F.B.I., and the U.S. Marshals Service all had special warrant units, using computer-mapping software, cell-phone tracking, and intelligence from every conceivable database: Social Security records, court records, hospital-admission records, electricity and gas bills, and employment records. “You hear them coming, that’s it, you gone,” Chuck tells his little brother. “Period. ’Cause whoever they looking for, even if it’s not you, nine times out of ten they’ll probably book you.” Goffman sometimes saw young children playing the age-old game of cops and robbers in the street, only the child acting the part of the robber wouldn’t even bother to run away:

I saw children give up running and simply stick their hands behind their back, as if in handcuffs; push their body up against a car without being asked; or lie flat on the ground and put their hands over their head. The children yelled, “I’m going to lock you up! I’m going to lock you up, and you ain’t never coming home!” I once saw a six-year-old pull another child’s pants down to do a “cavity search.”

When read alongside Ianni, what is striking about Goffman’s book is not the cultural difference between being an Italian thug in the early part of the twentieth century and being an African-American thug today. It’s the role of law enforcement in each era. Chuck’s high-school education ended prematurely after he was convicted of aggravated assault in a schoolyard fight. Another boy called Chuck’s mother a crack whore, and he pushed his antagonist’s face into the snow. In a previous generation, this dispute would not have ended up in the legal system. Until the nineteen-seventies, outstanding warrants in the city of Philadelphia were handled by a two-man team, who would sit in an office during the evening hours and make telephone calls to the homes of people on their list. Anyone stopped by the police could show a fake I.D. Today, there are computers and sometimes even fingerprint machines in squad cars. Between 1960 and 2000, the ratio of police officers to Philadelphia residents rose by almost seventy per cent.

In the previous era, according to Goffman, the police “turned a fairly blind eye” to prostitution, drug dealing, and gambling in poor black neighborhoods. But in the late nineteen-eighties, she writes, “corruption seems to have been largely eliminated as a general practice, at least in the sense of people working at the lower levels of the drug trade paying the police to leave them in peace.”

The entire piece is well worth the ten minutes it takes to read it. But it does seem the earlier immigrant crime families were able to climb a ladder to relative respectability that was never available to inner-city drug gangs.


Death by HR: How Affirmative Action Cripples OrganizationsDeath by HR: How Affirmative Action Cripples Organizations

[From Death by HR: How Affirmative Action Cripples Organizations,  available now in Kindle and trade paperback.]

The first review is in: by Elmer T. Jones, author of The Employment Game. Here’s the condensed version; view the entire review here.

Corporate HR Scrambles to Halt Publication of “Death by HR”

Nobody gets a job through HR. The purpose of HR is to protect their parent organization against lawsuits for running afoul of the government’s diversity extortion bureaus. HR kills companies by blanketing industry with onerous gender and race labor compliance rules and forcing companies to hire useless HR staff to process the associated paperwork… a tour de force… carefully explains to CEOs how HR poisons their companies and what steps they may take to marginalize this threat… It is time to turn the tide against this madness, and Death by HR is an important research tool… All CEOs should read this book. If you are a mere worker drone but care about your company, you should forward an anonymous copy to him.

 


More on Social Decay:

“Marriage Rate Lowest in a Century”
Making Divorce Hard to Strengthen Marriages?
The High Cost of Divorce
Divorced Men 8 Times as Likely to Commit Suicide as Divorced Women
Cuba: Where All but the Connected are Poor
“Postcards from Venezuela”
Ross Douthat on Unstable Families and Culture
“Income Inequality” Propaganda is Just Disguised Materialism
The Social Decay of Black Neighborhoods (And Yours!)
“Marriage Markets” – Marriage Beyond Our Means?
Real-Life “Hunger Games”: Soft Oppression Destroys the Poor
Why Did Black Crime Syndicates Fail to Go Legit?
“Why Are Great Husbands Being Abandoned?”
Public Schools in Poor Districts: For Control Not Education
Culture Wars: Peace Through Limited Government
Steven Pinker on Harvard and Meritocracy

“Breaking Bad”–The Lessons of Walter White

Pre-Exhaustion Weightlifting Routines: Study Shows No Improvement

Squats - the best compound exercise!

Squats – the best compound exercise!

Most studies of weightlifting are done on students or relative beginners; naturally the untrained will show a larger response than subjects who have been training for years.

Trainers have come up with a variety of complex routines to get experienced lifters past a plateau where they seem to be unable to make further gains. One of the more logical of these is Pre-Exhaustion (PreEx) training, which targets the strongest link muscle of a compound exercise with isolation exercise before the compound exercise, with the goal of saving the weak link muscles so that the compound exercise will fully exhaust the already-trained stronger muscle.

A new study, “The effects of pre-exhaustion, exercise order, and rest intervals in a full-body resistance training intervention” by James Peter Fisher, Luke Carlson, James Steele, and Dave Smith blows that out of the water. Fully-trained subjects were given either routines in proper order for PreEx training or routines not in such order. The result was that the order of exercise made no significant difference in gains or performance.

It is generally true that compound exercises are more time-efficient, and a series of compound exercises (like pullups, squats, or deadlifts) done with intensity and to exhaustion is likely to produce better gains in less workout time than a mix of isolation and compound exercises. There are reasons to do isolation exercises — when you do have a weak link needing further strengthening to catch up, or when injury reduces ability to do compound exercises — but they should not occupy much of your gym time.

Abstract:

Pre-exhaustion (PreEx) training is advocated on the principle that immediately preceding a compound exercise with an isolation exercise can target stronger muscles to pre-exhaust them to obtain greater adaptations in strength and size. However, research considering PreEx training method is limited. The present study looked to examine the effects of a PreEx training programme. Thirty-nine trained participants (male = 9, female = 30) completed 12 weeks of resistance training in 1 of 3 groups: a group that performed PreEx training (n = 14), a group that performed the same exercise order with a rest interval between exercises (n = 17), and a control group (n = 8) that performed the same exercises in a different order (compound exercises prior to isolation). No significant between-group effects were found for strength in chest press, leg press, or pull-down exercises, or for body composition changes. Magnitude of change was examined for outcomes also using effect size (ES). ESs for strength changes were considered large for each group for every exercise (ranging 1.15 to 1.62). In conclusion, PreEx training offers no greater benefit to performing the same exercises with rest between them compared with exercises performed in an order that prioritises compound movements.

Further discussion of PreEx:

Pre-exhaustion (PreEx) training is an advanced resistance training (RT) method where 2 or more sequential exercises are performed in immediate succession. Whilst Jones (1970) is often credited for the hypothesis and application of PreEx RT, he suggests that the original concept existed prior to his description. The PreEx method is based upon the hypothesis that a point of momentary muscular failure (MMF) in a compound exercise occurs when the weakest muscles involved are no longer able to apply the required force to continue the exercise (Jones 1970). As such the “target” muscles can be “pre-exhausted” with an isolation exercise before moving immediately to a compound exercise. For example, the biceps might be the “weak-link” in a pulling exercise though the target might be to train the latissimus muscles. With this in mind, it is suggested to pre-exhaust the target muscles using an isolation exercise immediately prior to a compound exercise. It is hypothesised that this provides greater stimulation to the target muscles. Jones (1970) notes that “during the brief period while your weak-link muscles are actually stronger than your target muscles, you can take advantage of that momentary condition to use the strength of the weak-link muscles to train the target muscles much harder than would otherwise be possible.”1 Since evidence suggests training to MMF maximally recruits motor units and produces greatest gains in muscular strength (Fisher et al. 2011) and hypertrophy (Fisher et al. 2013a), the notion of attaining a greater fatigue to maximise adaptation appears logical.